The result of the variant on RNA or protein purpose, based on experimental proof from submitters.
This benefit is calculated by NCBI dependant on information from submitters. Study our guidelines for calculating the review position. The number of submissions which add to this critique status is proven in parentheses.
There is absolutely no functional evidence in ClinVar for this variation. In case you have generated functional details for this variation, please look at publishing that knowledge to ClinVar.
This column includes more info supporting the classification, which include citations, the comment on classification, and detailed proof presented as observations in the variant by the submitter.
The ailment to the classification, provided by the submitter for this submitted (SCV) history. This column also contains the afflicted status and allele origin of individuals noticed with this variant.
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Read through our policies for calculating the evaluation position. This column also features a url on the submitter’s assertion requirements if supplied, and the gathering strategy.
The publishing Firm for this submitted (SCV) history. This column also features the SCV accession and Edition quantity, the day this SCV 1st appeared in ClinVar, and the date this SCV was final up-to-date in ClinVar.
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Stars symbolize the aggregate evaluate standing, or the level of evaluate supporting the mixture germline classification for this VCV record.
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